The Humanitarian and Resilience Investing (HRI) initiative was launched in 2019 to encourage flows of public and private capital into financially sustainable opportunities that benefit communities in humanitarian and fragile contexts.1 A core enabler to achieve scale and unlock private capital in these contexts is organizational readiness, which refers to the preparedness of an organization to undergo a major change or take on a significant new project. Humanitarian and resilience investing not only introduces new financial instruments but also develops new partnerships and business models that challenge mindsets and push the boundaries of what is possible within the existing rules and systems. If organizations are not ready,new initiatives are likely to fail, because barriers will discourage or defeat intrapreneurs (entrepreneurs within an established organization)2 to drive change.