Adolescent and youth account for one-third of the population in the United Republic of Tanzania (URT).1 The population of adolescents, ages 10–19, and youth, ages 20–24,2 is estimated to increase from 14.8 million (2013) to 28.2 million (2035). This cohort accounts for 32 percent of the population, however, there has been neither a systematic review on the quality of their lives nor an assessment on the extent to which their well-being has been changing over time. In 2021, the Government of Tanzania, under the auspices of the Ministry of Health, Community Development, Gender, Elderly and Children (MoHC￾DGEC), released the National Accelerated Action and Investment Agenda for Adolescent Health and Well-being (NAIA-AHW) aimed at highlighting the challenges faced by adolescents (ages 10–19) and defining the strategy for investment (MoHCDEC 2021). However, youth (ages 20–24) are not a part of this action plan. As this cohort continues to grow in number, it remains crucial to ensure they are being supported to reach their maximum potential. To highlight how best to harness the po￾tential of adolescents and youth in the URT, the World Bank has prepared a three-part series.3