Agriculture in the State of Mississippi is diverse. The industry employs nearly 29 percent of the state’s population and has a farm-gate value (i.e. market value of products minus selling costs) of USD 7.45 billion. The focus of this case study is interagency collaboration in Mississippi rather than a single approach, agency, or organization. Represented agencies fit into four broad approaches to developing agriculture human capital among youth and adults: (i) formal education system; (ii) nonformal education system; (iii) state governmental agencies; and (iv) advocacy and commodity groups. These agencies (e.g. primary and secondary schools, universities, Extension, state agencies, organizations and groups) work both individually and collaboratively to provide education, resources and services to diverse clients, including youth, adults, farmers, ranchers, producers, families, schools, businesses, organizations, industries and communities. Success is conceptualized as a synergistic environment where highly effective individual agencies work together to produce a greater effect than one agency can create on its own, enhancing agriculture human capital and the agriculture industry as a whole.